iTRAQ-based comparative proteomic analysis in different developmental stages of Echinococcus granulosus
نویسندگان
چکیده
منابع مشابه
A transcriptomic analysis of Echinococcus granulosus larval stages
Background: The cestode Echinococcus granulosus the agent of cystic echinococcosis, a zoonosis affecting humans and domestic animals worldwide is an excellent model for the study of host-parasite cross-talk that interfaces with two mammalian hosts. To develop the molecular analysis of these interactions, we carried out an EST survey of E. granulosus larval stages. We report the salient features...
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Echinococcus granulosus protoscolex proteins were separated using two-dimensional electrophoresis and then identified using mass spectrometry; we identified 61 proteins, 28 which are newly described of which 4 could be involved in hydatid cyst fertility molecular mechanisms.
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Cystic Echinococcosis is an important zoonosis in the sheep rising areas of Iran. To develop a simple and reliable diagnostic method for Echinococcus infection in definitive hosts, E. granulosus polyoclonal antibodies (PolyAbs) were prepared from adult worm in rabbit. A selected PoAb was used for coproantigen detection in faecal samples obtained from animals naturally infected with Echinococcus...
متن کاملA Transcriptomic Analysis of Echinococcus granulosus Larval Stages: Implications for Parasite Biology and Host Adaptation
BACKGROUND The cestode Echinococcus granulosus--the agent of cystic echinococcosis, a zoonosis affecting humans and domestic animals worldwide--is an excellent model for the study of host-parasite cross-talk that interfaces with two mammalian hosts. To develop the molecular analysis of these interactions, we carried out an EST survey of E. granulosus larval stages. We report the salient feature...
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ژورنال
عنوان ژورنال: Parasite
سال: 2021
ISSN: 1776-1042
DOI: 10.1051/parasite/2021012